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Lure of ANBR to rescue the Roc1a mutant, these results suggest that, within the context of the male germ linespecific Cul3 E3 ligase complex, the Roc1a RING domain can productively interact with the same E2s as Roc1b, while Roc1b cannot do so with all of the E2s that function with Roc1a. Interestingly, expression of wild type Roc1b from the Roc1a promoter was unable to rescue male sterility (Fig.

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