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Ells or compartments and induce mitosis of CSCs. Two mechanisms of AICP are known in Drosophila Melanogaster. One of these involves the JNK signaling pathway [74]. Interestingly, studies reveal JNK proteins to have a dual role: they can be either proto-oncogenes or tumor suppressors [75]. The first role may be due to stimulation of proliferation of CSCs, whereas tumor suppression may stem from JNK

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